Build where tech meets health.
UC Berkeley-based accelerator for early-stage healthcare startups
100+
startups accelerated
$370M+
raised by alumni companies
$1B+
portfolio valuation
Our Focus Areas
Medical Data Management
Artificial Intelligence & Machine Learning
Insurance Technology
Digital Platforms & SaaS
Revenue Cycle Management
Healthcare Security
Services
Founder Community
Engage with a dynamic network of founders who collaborate, share insights, and support one another on their entrepreneurial journey.
Weekly Standup
Learn, stay fresh, and get ideas and feedback by interacting weekly with other founders in the cohort .
Workshops
Practice pitching, get tangible technical support, and gain valuable insights by hearing from our esteemed mentors and guest speakers.
Grant Funding
Access grant funding through our partners like Roivant Sciences or SOMPO Digital Lab.
Clinical Connections
Connect with physician-scientists, healthcare key opinion leaders, and industry experts to optimize clinical success.
Investor Introductions
Meet potential investors in the healthcare and adjacent spaces through our robust network.
Designated Point Person
Direct any needs to a specially designated Health Engine member throughout the program.
Demo Day
Deliver your pitch and respond to questions from investors and industry experts in attendance.
Health Engine News
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Founder Series
Dr. Luis Pierpauli, founder of Gisens Biotech, sat down with Avaneesh Tisgaonkar from our team for Founder Series Episode 7 to discuss the future of at-home health monitoring via real-time graphene biosensors.
Dr. Pierpauli's expertise and drive really shine through in this episode, as he explains how we can enable more rapid, accurate, and decentralized kidney disease testing.
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Founder Series
In this episode, we sat down with Nathaniel Hundt to discuss how Dr. Katz, Inc. is building the infrastructure for the future of mental health. Nate opened up about what it’s actually like to build a venture from the ground up, sharing his insights on navigating healthcare IT and the level of perseverance it took to survive his first year as a solo founder.
With his background in enterprise software, Nate brings a unique perspective on how to standardize care across major health systems. -
SF Tech Week 2025
We're incredibly grateful to everyone who joined us for an inspiring night of ideas, collaboration, and community at the TECH WEEK by a16z X Health Engine Mixer last Tuesday.
A shoutout to our panelists Gregory V. Simpson, Ph.D. (CEO of Think Now, Inc.), Wei Escala (CEO of Eggschain, Inc.), Dr. Steve Pham (UCSF Department of Emergency Medicine), and Abrar Rahman (CEO of Dorsal.fyi) for their inspiring insights and energy. -
Founder Series
We sat down with Wei Escala, founder of Eggschain - a platform for guarding patients’ data using the Bitcoin blockchain.
Wei discussed her career leading to becoming a founder, the unique opportunities in healthcare today, and how she became the first person to put her own eggs on the blockchain! -
Fundraising
BioSapien (HE Cohort VI) raised $5.5M to begin clinical trials in the UAE for their cancer localization solution.
Their vision is to offer a fair fight to cancer patients by treating cancer at the tumor site using their flagship product: the MediChip. Think of it as a patch that can be applied at the cancer site to deliver chemotherapy locally rather than the current methods which are infamous for having severe on-target and off-target effects. -
Demo Day VII
Our 7th cohort included 11 startups revolutionizing the healthtech space!
From cancer screening to insurance verification API, the 11 startups pitched to some of the biggest investment firms in healthcare and tech.
Welcoming Cohort X
Health Engine’s Spring 2026 cohort includes companies building autonomous patient transport robotics, microbiome-driven drug discovery models, AI-powered mental health workflow platforms, and real-time hospital discharge coordination systems, and so much more.
Partners
